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2009
ElHajjaji H, DumoulinM, MatagneA, ColauD, RoosG, MessensJ, ColletJF.  2009.  The zinc center influences the redox and thermodynamic properties of Escherichia coli thioredoxin 2. 386(1):60-71. Abstract
2007
BarlowJN, SteyaertJ.  2007.  Examination of the mechanism and energetic contribution of leaving group activation in the purine-specific nucleoside hydrolase from Trypanosoma vivax. BBA. 1774(11):1451-1461. Abstract
GoeminneA, McNaughtonM, BalG, SurpateanuG, VanDerV, DeProl S, VerseesW, SteyaertJ, ApersS, HaemersA, AugustynsK.  2007.  1,2,3-Triazolylalkylribitol derivatives as nucleoside hydrolase inhibitors. Bioorg. & Med. Chem. Lett.. 17(9):2523-2526. Abstract
2006
VandemeulebrouckeA, VerseesW, SteyaertJ, BarlowJN.  2006.  Multiple transients in the pre-steady-state of nucleoside hydrolase reveal complex substrate binding, product base release, and two apparent rates of chemistry. Biochemistry. 45(30):9307-9318. Abstract
RoosG, ButsL, VanBelle K, BrosensE, GeerlingsP, LorisR, WynsL, MessensJ.  2006.  Interplay between ion binding and catalysis in the thioredoxin-coupled arsenate reductase family. J. Mol. Biol.. 360(4):826-838. Abstract
DeGenst E, SilenceK, DecanniereK, ConrathK, LorisR, KinneJ, MuyldermansS, WynsL.  2006.  Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies. 103(12):4586-4591. Abstract
2005
RanquinA, VerseesW, MeierW, SteyaertJ, VanGelder P.  2005.  Therapeutic nanoreactors: combining chemistry and biology in a novel triblock copolymer drug delivery system. Nanoletters. 5(11):2220-2224. Abstract
LoverixS, GeerlingsP, McNaughtonM, AugustynsK, VandemeulebrouckeA, SteyaertJ, VerseesW.  2005.  Substrate-assisted leaving group activation in enzyme-catalyzed N-glycosidic bond cleavage. J. Biol. Chem. 280(15):14799-14802. Abstract
DumoulinM, CanetD, LastAM, PardonE, ArcherDB, MuyldermansS, WynsL, MatagneA, RobinsonCV, RedfieldC, DobsonCM.  2005.  Reduced global cooperativity is a common feature underlying the amyloidogenicity of pathogenic lysozyme mutations. Nature. 346(3):773-788. Abstract
2004
MessensJ, VanMolleI, VanhaesebrouckP, LimbourgM, VanBelle K, WahniK, MartinsJC, LorisR, WynsL.  2004.  How thioredoxin can reduce a buried disulphide bond. J. Mol. Biol.. 339(3):527-537. Abstract
2003
VandemeulebrouckeA, VerseesW, DeVos S, VanHolsbeke E, SteyaertJ.  2003.  Pre-steady-state analysis of the nucleoside hydrolase of Trypanosoma vivax. Evidence for half-of-the-sites reactivity and rate-limiting product release. Biochemistry. 42(44):12902-12908. Abstract
CanetD, LyonCE, ScheekRM, RobillardGT, DobsonCM, HorePJ, van NulandNA.  2003.  Rapid formation of non-native contacts during the folding of HPr revealed by real-time photo-CIDNP NMR and stopped-flow fluorescence experiments. 330(2):397-407. Abstract
MessensJ, MartinsJC, ZegersI, VanBelle K, BrosensE, WynsL.  2003.  Purification of an oxidation-sensitive enzyme, pI258 arsenate reductase from Staphylococcus aureus. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.. 790(1-2):217-227. Abstract
VerseesW, VanHolsbeke E, DeVos S, DecanniereK, ZegersI, SteyaertJ.  2003.  Cloning, preliminary characterization and crystallization of nucleoside hydrolases from Caenorhabditis elegans and Campylobacter jejuni. Acta Crystallographica D. 59(Pt 6):1087-1089. Abstract
AzuagaAI, CanetD, SmeenkG, BerendsR, TitgemeijerF, DuurkensR, MateoPL, ScheekRM, RobillardGT, DobsonCM, van NulandNA.  2003.  Characterization of single-tryptophan mutants of histidine-containing phosphocarrier protein: evidence for local rearrangements during folding from high concentrations of denaturant. 42(17):4883-4895. Abstract
2002
MignonP, SteyaertJ, LorisR, GeerlingsP, LoverixS.  2002.  A nucleophile activation dyad in ribonucleases. A combined X-ray crystallographic/ab initio quantum chemical study. Journal Bioogical Chemistry. 277(39):36770-36774. Abstract
MessensJ, MartinsJC, VanBelle K, BrosensE, DesmyterA, DeGieter M, WieruszeskiJM, WillemR, WynsL, ZegersI.  2002.  All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade. Proc. Natl. Acad. Sci. USA. 99(13):8506-8511. Abstract
VerseesW, DecanniereK, VanHolsbeke E, DevroedeN, SteyaertJ.  2002.  Enzyme-substrate interactions in the purine-specific nucleoside hydrolase from Trypanosoma vivax. J. Biol. Chem. 277(18):15938-15946. Abstract
Dao-ThiMH, CharlierD, LorisR, MaesD, MessensJ, WynsL, BackmannJ.  2002.  Intricate interactions within the ccd plasmid addiction system. J. Biol. Chem.. 277(5):3733-3742. Abstract
MessensJ, MartinsJC, BrosensE, VanBelle K, JacobsDM, WillemR, WynsL.  2002.  Kinetics and active site dynamics of Staphylococcus aureus arsenate reductase. J. Biol. Inorg. Chem.. 7(1-2):146-156. Abstract
2001
DeVos S, BackmannJ, PrevostM, SteyaertJ, LorisR.  2001.  Hydrophobic core manipulations in ribonuclease T1. Biochemistry. 40(34):10140-10149. Abstract
ReaderJS, van NulandNA, ThompsonGS, FergusonSJ, DobsonCM, RadfordSE.  2001.  A partially folded intermediate species of the beta-sheet protein apo-pseudoazurin is trapped during proline-limited folding. 10(6):1216-1224. Abstract
LoverixS, SteyaertJ.  2001.  Deciphering the mechanism of RNase T1. 341:305-323.
2000
LoverixS, WinqvistA, StrombergR, SteyaertJ.  2000.  Mechanism of RNase T1: concerted triester-like phosphoryl transfer via a catalytic three-centered hydrogen bond. 7(8):651-658. Abstract
BouckaertJ, DewallefY, PoortmansF, WynsL, LorisR.  2000.  The structural features of concanavalin A governing non-proline peptide isomerization. 275(26):19778-19787. Abstract

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