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ButsL, Garcia-PinoA, ImbertyA, AmiotN, BoonsGJ, BeeckmansS, VerseesW, WynsL, LorisR.  2006.  Structural basis for the recognition of complex-type biantennary oligosaccharides by Pterocarpus angolensis lectin. 273(11):2407-2420. Abstract
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GoeminneA, McNaughtonM, BalG, SurpateanuG, VanDerV, DeProl S, VerseesW, SteyaertJ, HaemersA, AugustynsK.  2008.  Synthesis and biochemical evaluation of guanidino-alkyl-ribitol derivatives as nucleoside hydrolase inhibitors. Eur. Journ. Med. Chem.. 43(2):315-326. Abstract
GoeminneA, McNaughtonM, BalG, SurpateanuG, VanDerV, DeProl S, VerseesW, SteyaertJ, HaemersA, AugustynsK.  2007.  Synthesis and biochemical evaluation of guanidino-alkyl-ribitol derivatives as nucleoside hydrolase inhibitors. Abstract
GoeminneA, McNaughtonM, BalG, SurpateanuG, VanDerV, DeProl S, VerseesW, SteyaertJ, ApersS, HaemersA, AugustynsK.  2007.  1,2,3-Triazolylalkylribitol derivatives as nucleoside hydrolase inhibitors. Bioorg. & Med. Chem. Lett.. 17(9):2523-2526. Abstract
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LoverixS, GeerlingsP, McNaughtonM, AugustynsK, VandemeulebrouckeA, SteyaertJ, VerseesW.  2005.  Substrate-assisted leaving group activation in enzyme-catalyzed N-glycosidic bond cleavage. J. Biol. Chem. 280(15):14799-14802. Abstract
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RanquinA, VerseesW, MeierW, SteyaertJ, VanGelder P.  2005.  Therapeutic nanoreactors: combining chemistry and biology in a novel triblock copolymer drug delivery system. Nanoletters. 5(11):2220-2224. Abstract
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SpaepenS, VerseesW, GockeD, PohlM, SteyaertJ, VanderleydenJ.  2007.  Characterization of phenylpyruvate decarboxylase, involved in auxin production of Azospirillum brasilense. Journal of Bacteriology. 189(21):7626-7633. Abstract
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VerseesW, SpaepenS, WoodMD, LeeperFJ, VanderleydenJ, SteyaertJ.  2007.  Molecular mechanism of allosteric substrate activation in a thiamine diphosphate-dependent decarboxylase. Journal Biological Chemistry. 282(48):35269-35278. Abstract
VerseesW, SpaepenS, VanderleydenJ, SteyaertJ.  2007.  The crystal structure of phenylpyruvate decarboxylase from Azospirillum brasilense at 1.5 A resolution. Implications for its catalytic and regulatory mechanism. FEBS J. 274(9):2363-2375. Abstract
VandemeulebrouckeA, VerseesW, SteyaertJ, BarlowJN.  2006.  Multiple transients in the pre-steady-state of nucleoside hydrolase reveal complex substrate binding, product base release, and two apparent rates of chemistry. Biochemistry. 45(30):9307-9318. Abstract
VerseesW, BarlowJ, SteyaertJ.  2006.  Transition-state complex of the purine-specific nucleoside hydrolase of T. vivax: enzyme conformational changes and implications for catalysis. Journal Molecular Biology. 359(2):331-346. Abstract
VerseesW, LoverixS, VandemeulebrouckeA, GeerlingsP, SteyaertJ.  2004.  Leaving group activation by aromatic stacking: an alternative to general acid catalysis. J. Mol. Biol. 338(1):1-6. Abstract
VandemeulebrouckeA, VerseesW, DeVos S, VanHolsbeke E, SteyaertJ.  2003.  Pre-steady-state analysis of the nucleoside hydrolase of Trypanosoma vivax. Evidence for half-of-the-sites reactivity and rate-limiting product release. Biochemistry. 42(44):12902-12908. Abstract
VerseesW, SteyaertJ.  2003.  Catalysis by nucleoside hydrolases. Current opinion in structural biology. 13(6):731-738. Abstract
VerseesW, VanHolsbeke E, DeVos S, DecanniereK, ZegersI, SteyaertJ.  2003.  Cloning, preliminary characterization and crystallization of nucleoside hydrolases from Caenorhabditis elegans and Campylobacter jejuni. Acta Crystallographica D. 59(Pt 6):1087-1089. Abstract
Versees Wim, Decanniere Klaas, Van Holsbeke Els, Devroede Neel, Steyaert Jan.  2002.  Enzyme-Substrate Interactions in the Purine-specific Nucleoside Hydrolase from Trypanosoma vivax. J. Biol. Chem.. 277:15938-15946. Abstract
VerseesW, DecanniereK, VanHolsbeke E, DevroedeN, SteyaertJ.  2002.  Enzyme-substrate interactions in the purine-specific nucleoside hydrolase from Trypanosoma vivax. J. Biol. Chem. 277(18):15938-15946. Abstract
VerseesW, DecanniereK, PelleR, DepoorterJ, BrosensE, ParkinDW, SteyaertJ.  2001.  Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax. 307(5):1363-1379. Abstract


Prof. Wim Versées