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[Report] Signaling Kinase AMPK Activates Stress-Promoted Transcription via Histone H2B Phosphorylation
Fri, 09/03/2010 - 02:00The energy sensor AMPK facilitates gene transcription by localizing to chromatin and phosphorylating histone H2B.
Authors: David Bungard, Benjamin J. Fuerth, Ping-Yao Zeng, Brandon Faubert, Nancy L. Maas, Benoit Viollet, David Carling, Craig B. Thompson, Russell G. Jones, Shelley L. Berger
Categories: Journals
[Report] The Junctional Adhesion Molecule JAML Is a Costimulatory Receptor for Epithelial γδ T Cell Activation
Fri, 09/03/2010 - 02:00A costimulatory receptor for immune cells in the skin is identified.
Authors: Deborah A. Witherden, Petra Verdino, Stephanie E. Rieder, Olivia Garijo, Robyn E. Mills, Luc Teyton, Wolfgang H. Fischer, Ian A. Wilson, Wendy L. Havran
Categories: Journals
[Report] The Molecular Interaction of CAR and JAML Recruits the Central Cell Signal Transducer PI3K
Fri, 09/03/2010 - 02:00Ligand engagement and initiation of signaling has been imaged for a costimulatory receptor for immune cells in the skin.
Authors: Petra Verdino, Deborah A. Witherden, Wendy L. Havran, Ian A. Wilson
Categories: Journals
[Report] Glutamine Deamidation and Dysfunction of Ubiquitin/NEDD8 Induced by a Bacterial Effector Family
Fri, 09/03/2010 - 02:00Pathogenic bacterial proteins interfere with eukaryotic ubiquitination pathways to induce cytopathic effects.
Authors: Jixin Cui, Qing Yao, Shan Li, Xiaojun Ding, Qiuhe Lu, Haibin Mao, Liping Liu, Ning Zheng, She Chen, Feng Shao
Categories: Journals
New Products
Fri, 09/03/2010 - 02:00A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.
Categories: Journals
[Podcast] Science Podcast
Fri, 09/03/2010 - 02:00The show includes how social network structure affects the spread of behavior, challenging the mammoth-killer impact hypothesis, your letters to Science, and more.
Categories: Journals
This Week in Science
Fri, 08/27/2010 - 02:00Human Adenovirus Structures | Improving Earth Models | Swelling Pores | Ant Variation | Environment Matters | Two Heads Are Better Than One | Forced Open | Black Holes as Tools | Cracking Up | Over the Moon | Toward a General Flu Vaccination | Making Roots | Plants' Modified SOS Call | Intracellular pH and Lipid Metabolism
Categories: Journals
Editors' Choice
Fri, 08/27/2010 - 02:00Psychology: Religion and Togetherness | Cancer: Undesirable Consequences | Applied Physics: Mapping Microwaves | Chemistry: Electron Turnstile
Categories: Journals
Random Samples
Fri, 08/27/2010 - 02:00One Short Stroll for Mankind | Math Prizes Multiply | Whisky in the Car?
Categories: Journals
[Editorial] What Is STEM Education?
Fri, 08/27/2010 - 02:00Author: Rodger W. Bybee
Categories: Journals
[News of the Week] Chronic Fatigue Syndrome: New XMRV Paper Looks Good, Skeptics Admit—Yet Doubts Linger
Fri, 08/27/2010 - 02:00This week, a long-awaited paper about the link between a virus and chronic fatigue syndrome (CFS) finally saw the light of day. The study confirms a controversial 2009 paper that reported CFS patients are often infected with the virus, called XMRV.
Author: Martin Enserink
Categories: Journals
[News of the Week] Marine Ecology: Hard Summer for Corals Kindles Fears for Survival of Reefs
Fri, 08/27/2010 - 02:00Coral reefs are reeling from extensive bleaching in the Indian Ocean and throughout Southeast Asia. And although some hard-hit areas have cooled—offering hope that some reefs may rebound—other regions are just now heating up.
Author: Dennis Normile
Categories: Journals
[News of the Week] China: Astronomers Hope Their Prize Telescope Isn't Blinded by the Light
Fri, 08/27/2010 - 02:00Chinese astronomers thought they had their hands full, fine-tuning their complicated new survey telescope into next year. Now they have a more urgent problem: Light pollution could jeopardize its ambitious science program.
Author: Richard Stone
Categories: Journals
[News of the Week] Research Facilities: U.S. Physicists Eye Australia for New Site of Gravitational-Wave Detector
Fri, 08/27/2010 - 02:00U.S. physicists want to take parts from their massive twin gravitational-wave detectors and use them to build a third detector near Perth in western Australia, greatly enhancing the experiment's ability to pinpoint sources of gravitational waves, should such waves ever be spotted.
Author: Adrian Cho
Categories: Journals
[News of the Week] Cell Biology: To Scientists' Dismay, Mixed-Up Cell Lines Strike Again
Fri, 08/27/2010 - 02:00Over the past 5 years, a handful of research teams have found that mesenchymal stem cells (MSCs) could become cancerlike after growing for months in the lab. But three of these research teams have now discovered that the cancerlike cells they spotted are unrelated to the original MSCs.
Author: Gretchen Vogel
Categories: Journals
[News of the Week] ScienceNOW.org: From Science's Online Daily News Site
Fri, 08/27/2010 - 02:00ScienceNOW reported this week that martian volcano mud may have hosted life, zombies thrived on ancient Earth, hair follicles track the body's clock, and bacteria are gobbling gulf oil, among other stories.
Categories: Journals
[News of the Week] Chemistry: Organizers Panned for Omitting Israelis From Meeting in Jordan
Fri, 08/27/2010 - 02:00Political tensions between Israel and the Arab world are threatening to overshadow an upcoming chemistry conference in Jordan. The verbal sparring has already created plenty of raw feelings and led to much finger-pointing.
Author: Robert F. Service
Categories: Journals
[News of the Week] U.S. Science Policy: NSF Turns Math Earmark on Its Ear to Fund New Institute
Fri, 08/27/2010 - 02:00The National Science Foundation has quietly folded a recent earmark into a competitive grants program, eliminating what seemed to be one state's advantage.
Author: Jeffrey Mervis
Categories: Journals
[News of the Week] ScienceInsider: From the Science Policy Blog
Fri, 08/27/2010 - 02:00ScienceInsider reported this week that a court decision earlier this week temporarily blocking federal funding for work with human embryonic stem cells has left some researchers working with the cells facing a cutoff of funding, among other stories.
Categories: Journals
[News Focus] Archaeology: Google Earth Shows Clandestine Worlds
Fri, 08/27/2010 - 02:00Archaeologists are using Google's eye in the sky to bring covert activities to light, from prison building at Guantánamo Bay to looting in the Middle East.
Author: Heather Pringle
Categories: Journals