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Nature Strucural & Molecular Biology
Take a break
Wed, 07/07/2010 - 02:00Take a break
Nature Structural & Molecular Biology 17, 779 (2010). doi:10.1038/nsmb0710-779
For many reasons, scientists take a career break lasting from months to several years. Many eventually return but lose their place on the career ladder, working at a level far below their qualifications and talents. Signs of improved access for returners are hugely encouraging.
Categories: Journals
Research highlights
Wed, 07/07/2010 - 02:00Research highlights
Nature Structural & Molecular Biology 17, 780 (2010). doi:10.1038/nsmb0710-780
Categories: Journals
Dynamic structure of membrane-anchored Arf•GTP
Sat, 07/03/2010 - 23:00Dynamic structure of membrane-anchored Arf•GTP
Nature Structural & Molecular Biology 17, 876 (2010). doi:10.1038/nsmb.1853
Authors: Yizhou Liu, Richard A Kahn & James H Prestegard
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Crystal structure of the conserved herpesvirus fusion regulator complex gH–gL
Sat, 07/03/2010 - 23:00Crystal structure of the conserved herpesvirus fusion regulator complex gH–gL
Nature Structural & Molecular Biology 17, 882 (2010). doi:10.1038/nsmb.1837
Authors: Tirumala K Chowdary, Tina M Cairns, Doina Atanasiu, Gary H Cohen, Roselyn J Eisenberg & Ekaterina E Heldwein
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iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution
Sat, 07/03/2010 - 23:00iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution
Nature Structural & Molecular Biology 17, 909 (2010). doi:10.1038/nsmb.1838
Authors: Julian König, Kathi Zarnack, Gregor Rot, Tomaž Curk, Melis Kayikci, Blaž Zupan, Daniel J Turner, Nicholas M Luscombe & Jernej Ule
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Structural and functional insights into 5′-ppp RNA pattern recognition by the innate immune receptor RIG-I
Sat, 06/26/2010 - 23:00Structural and functional insights into 5′-ppp RNA pattern recognition by the innate immune receptor RIG-I
Nature Structural & Molecular Biology 17, 781 (2010). doi:10.1038/nsmb.1863
Authors: Yanli Wang, Janos Ludwig, Christine Schuberth, Marion Goldeck, Martin Schlee, Haitao Li, Stefan Juranek, Gang Sheng, Ronald Micura, Thomas Tuschl, Gunther Hartmann & Dinshaw J Patel
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Structure of Rev-erbα bound to N-CoR reveals a unique mechanism of nuclear receptor–co-repressor interaction
Sat, 06/26/2010 - 23:00Structure of Rev-erbα bound to N-CoR reveals a unique mechanism of nuclear receptor–co-repressor interaction
Nature Structural & Molecular Biology 17, 808 (2010). doi:10.1038/nsmb.1860
Authors: Caroline A Phelan, Robert T Gampe, Millard H Lambert, Derek J Parks, Valerie Montana, Jane Bynum, Timothy M Broderick, Xiao Hu, Shawn P Williams, Robert T Nolte & Mitchell A Lazar
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Determinants of structural and functional plasticity of a widely conserved protease chaperone complex
Sat, 06/26/2010 - 23:00Determinants of structural and functional plasticity of a widely conserved protease chaperone complex
Nature Structural & Molecular Biology 17, 837 (2010). doi:10.1038/nsmb.1839
Authors: Melisa Merdanovic, Nicolette Mamant, Michael Meltzer, Simon Poepsel, Alexandra Auckenthaler, Rie Melgaard, Patrick Hauske, Luitgard Nagel-Steger, Anthony R Clarke, Markus Kaiser, Robert Huber & Michael Ehrmann
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HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues
Sat, 06/26/2010 - 23:00HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues
Nature Structural & Molecular Biology 17, 844 (2010). doi:10.1038/nsmb.1840
Authors: Tobias Krojer, Justyna Sawa, Robert Huber & Tim Clausen
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Following the intersubunit conformation of the ribosome during translation in real time
Sat, 06/19/2010 - 23:00Following the intersubunit conformation of the ribosome during translation in real time
Nature Structural & Molecular Biology 17, 793 (2010). doi:10.1038/nsmb.1828
Authors: Colin Echeverría Aitken & Joseph D Puglisi
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RNA-mediated displacement of an inhibitory snRNP complex activates transcription elongation
Sat, 06/19/2010 - 23:00RNA-mediated displacement of an inhibitory snRNP complex activates transcription elongation
Nature Structural & Molecular Biology 17, 815 (2010). doi:10.1038/nsmb.1827
Authors: Iván D'Orso & Alan D Frankel
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Ion/substrate-dependent conformational dynamics of a bacterial homolog of neurotransmitter:sodium symporters
Sat, 06/19/2010 - 23:00Ion/substrate-dependent conformational dynamics of a bacterial homolog of neurotransmitter:sodium symporters
Nature Structural & Molecular Biology 17, 822 (2010). doi:10.1038/nsmb.1854
Authors: Derek P Claxton, Matthias Quick, Lei Shi, Fernanda Delmondes de Carvalho, Harel Weinstein, Jonathan A Javitch & Hassane S Mchaourab
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Accessibility of the Drosophila genome discriminates PcG repression, H4K16 acetylation and replication timing
Sat, 06/19/2010 - 23:00Accessibility of the Drosophila genome discriminates PcG repression, H4K16 acetylation and replication timing
Nature Structural & Molecular Biology 17, 894 (2010). doi:10.1038/nsmb.1825
Authors: Oliver Bell, Michaela Schwaiger, Edward J Oakeley, Florian Lienert, Christian Beisel, Michael B Stadler & Dirk Schübeler
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Protein refolding is required for assembly of the type three secretion needle
Sat, 06/12/2010 - 23:00Protein refolding is required for assembly of the type three secretion needle
Nature Structural & Molecular Biology 17, 788 (2010). doi:10.1038/nsmb.1822
Authors: Ömer Poyraz, Holger Schmidt, Karsten Seidel, Friedmar Delissen, Christian Ader, Hezi Tenenboim, Christian Goosmann, Britta Laube, Andreas F Thünemann, Arturo Zychlinsky, Marc Baldus, Adam Lange, Christian Griesinger & Michael Kolbe
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A unique secondary-structure switch controls constitutive gene repression by retinoic acid receptor
Sat, 06/12/2010 - 23:00A unique secondary-structure switch controls constitutive gene repression by retinoic acid receptor
Nature Structural & Molecular Biology 17, 801 (2010). doi:10.1038/nsmb.1855
Authors: Albane le Maire, Catherine Teyssier, Cathie Erb, Marina Grimaldi, Susana Alvarez, Angel R de Lera, Patrick Balaguer, Hinrich Gronemeyer, Catherine A Royer, Pierre Germain & William Bourguet
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Structural changes in a marine podovirus associated with release of its genome into Prochlorococcus
Sat, 06/12/2010 - 23:00Structural changes in a marine podovirus associated with release of its genome into Prochlorococcus
Nature Structural & Molecular Biology 17, 830 (2010). doi:10.1038/nsmb.1823
Authors: Xiangan Liu, Qinfen Zhang, Kazuyoshi Murata, Matthew L Baker, Matthew B Sullivan, Caroline Fu, Matthew T Dougherty, Michael F Schmid, Marcia S Osburne, Sallie W Chisholm & Wah Chiu
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Role for the MOV10 RNA helicase in Polycomb-mediated repression of the INK4a tumor suppressor
Sat, 06/12/2010 - 23:00Role for the MOV10 RNA helicase in Polycomb-mediated repression of the INK4a tumor suppressor
Nature Structural & Molecular Biology 17, 862 (2010). doi:10.1038/nsmb.1824
Authors: Selma El Messaoudi-Aubert, James Nicholls, Goedele N Maertens, Sharon Brookes, Emily Bernstein & Gordon Peters
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An aqueous H+ permeation pathway in the voltage-gated proton channel Hv1
Sat, 06/12/2010 - 23:00An aqueous H+ permeation pathway in the voltage-gated proton channel Hv1
Nature Structural & Molecular Biology 17, 869 (2010). doi:10.1038/nsmb.1826
Authors: I Scott Ramsey, Younes Mokrab, Ingrid Carvacho, Zara A Sands, Mark S P Sansom & David E Clapham
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Human mitochondrial mTERF wraps around DNA through a left-handed superhelical tandem repeat
Sat, 06/12/2010 - 23:00Human mitochondrial mTERF wraps around DNA through a left-handed superhelical tandem repeat
Nature Structural & Molecular Biology 17, 891 (2010). doi:10.1038/nsmb.1859
Authors: Nereida Jiménez-Menéndez, Pablo Fernández-Millán, Anna Rubio-Cosials, Carme Arnan, Julio Montoya, Howard T Jacobs, Pau Bernadó, Miquel Coll, Isabel Usón & Maria Solà
The regulation of mitochondrial DNA (mtDNA) processes is slowly being characterized at a structural level. We present here crystal structures of human mitochondrial regulator mTERF, a transcription termination factor also implicated in replication pausing, in complex with double-stranded DNA oligonucleotides containing the tRNALeuUUR gene sequence. mTERF comprises nine left-handed helical tandem repeats that form a left-handed superhelix, the Zurdo domain.
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Structural basis of G-tract recognition and encaging by hnRNP F quasi-RRMs
Sat, 06/05/2010 - 23:00Structural basis of G-tract recognition and encaging by hnRNP F quasi-RRMs
Nature Structural & Molecular Biology 17, 853 (2010). doi:10.1038/nsmb.1814
Authors: Cyril Dominguez, Jean-François Fisette, Benoit Chabot & Frédéric H-T Allain
Categories: Journals